Kanna (Sceletium tortuosum): Botanical Raw Material & Standardized Extracts

Discover our curated range of Kanna (Sceletium tortuosum)—a South African succulent with a well-documented ethnobotanical history and a growing modern research profile. We supply Kanna as traditional raw material and as precisely characterized extracts (ratio and standardized), enabling reliable, repeatable results for botanical study, analytical work, and technical applications.

Why Choose Our Kanna?

• Quality first: Every batch is analyzed for identity, alkaloid profile, and purity using modern methods such as HPLC. We screen for microbiology, heavy metals, and pesticide residues to meet strict specifications. PubMed

• Traceable & consistent: Batch documentation and supplier transparency ensure reproducibility for labs and serious hobbyists.

• Format flexibility: From raw plant material to standardized and ratio extracts, you can select the form that best suits your intended research protocol.

What is Kanna?

Kanna (Sceletium tortuosum) is a perennial succulent from the dry, rocky regions of South Africa’s Western and Northern Cape. It contains a suite of mesembrine-type alkaloids (e.g., mesembrine, mesembrenone, Δ7-mesembrenone) that are the focus of phytochemical and neuropharmacology research today. PubMed+1

Note: We supply Kanna strictly for technical, botanical, and research use. It is not a food, supplement, feed, or medicine and is not intended for consumption.

Shop Kanna by Format

Raw Material

Kanna (Sceletium tortuosum) — finely milled or crushed plant material suitable for classical botanical work, extraction method development, and QC benchmarking.

Ratio Extracts

• Kanna (Sceletium tortuosum) 50:1 — produced from ~50 parts plant material to 1 part finished extract for concentrated research applications.

• Kanna (Sceletium tortuosum) 100:1 — a higher-ratio concentrate for workflows that require smaller sample masses while maintaining a robust phytochemical fingerprint.

Ratio values indicate the input plant mass : final extract mass and do not by themselves specify alkaloid percentage.

Standardized Extracts

• Kanna (Sceletium tortuosum) standardized 0.4%

• Kanna (Sceletium tortuosum) standardized 3%

• Kanna (Sceletium tortuosum) standardized 5%

These extracts are manufactured to a defined total alkaloid content, supporting cross-batch comparability and method validation. Growing literature also explores standardized Sceletium extracts in controlled settings, including safety/tolerability and neuroimaging endpoints. PubMed+1

Our Quality & Testing Approach

• Identity & profile: HPLC assays characterize mesembrine-type alkaloids for identity and lot-to-lot consistency. PubMed

• Contaminant controls: Microbial counts, heavy metals, and pesticide residues are checked against internal thresholds before release.

• Documentation: Each batch is traceable, with COA data available upon request.

Research Snapshot (for context)

• Phytochemistry: Peer-reviewed work documents HPLC quantification and variability of mesembrine-type alkaloids across Sceletium materials and cultivation conditions. PubMed+1

• Human studies (standardized extracts):

  • fMRI (double-blind, placebo-controlled): Acute administration of a standardized Sceletium extract reduced anxiety-related amygdala activity and amygdala–hypothalamus coupling in healthy adults. Nature+1

  • Safety/tolerability: 8 mg and 25 mg daily were well tolerated over 3 months in healthy participants (double-blind, placebo-controlled). PubMed

  • Laboratory stress models: Single-dose studies reported reduced anxiety responding under stress tasks in healthy volunteers. PubMed+1

• Toxicology: Formal in-vivo toxicological assessment supports a favorable safety profile for a standardized extract under tested conditions. ScienceDirect

Important: The studies above are provided for scientific context only and do not constitute health claims about our products.

Who is this for?

• Botanical researchers validating methods

• QC labs building reference libraries

• Formulators evaluating extract formats (non-ingestible prototyping)

• Educators demonstrating chromatographic techniques and phytochemical profiling

FAQs

What’s the difference between a ratio extract and a standardized extract?
A ratio extract (e.g., 50:1, 100:1) describes how much starting plant material is used to make the final extract; it does not specify alkaloid %. A standardized extract declares a target alkaloid content (e.g., 0.4%, 3%, 5%), supporting better cross-batch comparability.

Do you provide Certificates of Analysis (COAs)?
Yes—COAs with alkaloid profiling (e.g., HPLC) and contaminant screens are available per batch.

Are these products for ingestion?
No. All Kanna products here are for technical, botanical, and research purposes only—not foods, supplements, animal feed, or medicines, and not intended for consumption.